The Regeneration of F1 Host Cell Spleen and Thymus at Ectopic Sites in F1 Animals Induced by Implantation of Parental Spleen and Thymus
نویسنده
چکیده
The ability of parental to F(1) spleen grafts to regenerate was equal to that of parental to parental or to F(1) or F(1) spleen grafts. Cytotoxicity analysis of parental to F(1) spleen and thymic grafts indicated that these "regenerated grafts" were composed of F(1) lymphocytes. Regenerated parental to F(1) spleen grafts were incapable of producing runt disease in newborn F(1) animals.
منابع مشابه
THE REGENERATION OF F1 HOST CELL SPLEEN AND TItYMUS AT ECTOPIC SITES IN Fx ANIMALS INDUCED BY IMPLANTA- TION OF PARENTAL SPLEEN AND THYMUS* BY IRA GREEN,~ M.D
The inductive regeneration of complete organs is not thought to occur in adults of higher animals. The fact that this phenomenon can take place in the case of murine spleen and thymus is the subject of this report. Previous investigators had noted that autologous mammalian spleen and thymus could regenerate after ectopic transplantation (1-4). However, the cell origin of the lymphocytes present...
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 119 شماره
صفحات -
تاریخ انتشار 1964